The project is focusing on the Syriac Galen Palimpsest (SGP), an extremely valuable multi-layered medieval manuscript containing a Syriac translation of Galen's main pharmacological treatise, 'On Simple Drugs', as the erased undertext. The manuscript is kept in a private collection in the USA, it has been fully digitised using multispectral technology and the results were made freely available online on the dedicated website. The project aims to create the critical edition of Galen’s text in Syriac based on the SGP through the advanced methods in image analysis and the bilingual Graeco-Syriac corpus on Sketch Engine platform.